Profile Dr. Antonella Di Pizio


 

 

 

Independent Research Group Leader - Computational Pharmacology

 

Lise-Meitner-Str. 34
85354 Freising
Germany

Tel.: +49 8161 71-2904

Email  ORCID  Curriculum Vitae

Research Interests:

  • Modeling chemosensory GPCRs to understand the molecular bases of ligand recognition and activation mechanism
  • Developing structure-based ligand design protocols to identify new taste- and odor-active compounds
  • Using chemoinformatics and structural bioinformatics approaches to investigate the combinatorial code of chemosensory perception

Selected Publications:

Di Pizio A, Behrens M, Krautwurst D. (2019) International Journal of Molecular Sciences, DOI: 10.3390/ijms20061402. Beyond the flavor: the potential druggability of chemosensory GPCRs

Nowak S, Di Pizio A, Levit A, Niv MY, Meyerhof W, Behrens M (2018) Biochim Biophys Acta, Gen Subj 1862, 2162-2173. Reengineering the ligand sensitivity of the broadly tuned human bitter taste receptor TAS2R14

Di Pizio A, Ben Shoshan-Galeczki Y, Hayes JE, Niv MY. (2018) Neuroscience Letters, DOI: 10.1016/j.neulet.2018.04.027. Bitter and sweet tasting molecules: it's complicated

Di Pizio A, Shy N, Behrens M, Meyerhof W, Niv MY. (2017) Frontiers in Molecular Biosciences, DOI: 10.3389/fmolb.2018.00006. Molecular features underlying selectivity in chicken bitter taste receptors

Di Pizio A, Kruetzfeldt LM, Cheled-Shoval S, Meyerhof W, Behrens M, Niv MY. (2017) Scientific Reports, DOI: 10.1038/s41598-017-08344-9. Ligand binding modes from low resolution GPCR models and mutagenesis: chicken bitter taste receptor as a test-case

 

For further papers please see ORCID

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