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Kurzprofil PD Dr. Maik Behrens
Leiter der Arbeitsgruppe Taste & Odor Systems Reception
Lise-Meitner-Str. 34
85354 Freising
Germany
Tel.: +49 8161 71-2987
- Understanding the molecular basis of human taste perception
- Structure-function analyses of taste receptors – can we predict taste modifiers de novo?
- Physiological functions of extra-oral taste receptors – are tastants drugs?
- Evolution of taste receptors – how did nutritional habits evolve?
- Discovery of taste modifiers and mixture effects – how are complex food items perceived?
| 2018 – current |
Leibniz-Institute of Food Systems Biology at the TU Munich, Freising Group leader Taste & Odor Systems Reception |
| Habilitation (2013) | University of Potsdam, Potsdam |
| 2000 – 2018 |
German Institute of Human Nutrition Potsdam-Rehbruecke, Nuthetal Senior Scientist Dept. Molecular Genetics |
| 1997 – 2000 |
University of Maryland, Baltimore, MD, USA Postdoctoral fellow School of Medicine, Dept. of Anatomy and Neurobiology |
| Dr. rer. nat. (1997) | University of Hamburg, Hamburg |
| 1993 – 1996 |
University of Hamburg, Hamburg Ph.D. student School of Medicine, Institute for Cell Biochemistry and Clinical Neurobiology Diploma Biology (1993) University of Hamburg, Hamburg |
| 1996 | Best Dissertation in Biology University of Hamburg, Hamburg |
| 2011 - 2014 | Program committee member AChemS |
| 2009 - 2018 | Editorial board member World Journal of Biological Chemistry |
| 2011 - current | Academic editor PLoS One |
| 2014 - current | Editorial board member Chemical Senses |
| 2019 - current | Specialist advisor HUGO Gene Nomenclature Committee |
| 2002 – 2017 | Lecture & Seminar “Cellular Signal Transduction”, University of Potsdam |
| 2016 – 2017 | Lecture “Functional Anatomy and Physiology of Inner Organs”, University of Potsdam |
| 2017 – 2018 | Lecture “Molecular Sensory Science” |
| 2019 – current | Lecture “Chemosensory Perception”, TU Munich |
| 2019 – current | Seminar “Recent Advances in Chemosensory Research”, TU Munich |
| 2002 – 2014 | Practical courses in Zoology, Molecular Genetics & Cellular Signal Transduction, University of Potsdam |
| 2020 – current | Internship “Chemosensory Perception” |
| 2001 – current | Supervision of 10 Ph.D. students, 1 Diploma student, 3 Master students, 7 Bachelor students, University of Potsdam & TU Munich |
(See ORCID for complete list)
1. Behrens, M.*, Foerster, S., Staehler, F., Raguse, J.-D., and Meyerhof, W. (2007) Gustatory expression pattern of the human TAS2R bitter receptor gene family reveals a heterogenous population of bitter responsive taste receptor cells. J. Neurosci., 27, 12630-12640.
2. Meyerhof, W.*, Batram, C., Kuhn, C., Brockhoff, A., Chudoba, E., Bufe, B., Appendino, G., and Behrens, M. (2010) The molecular receptive ranges of human TAS2R bitter taste receptors. Chem. Senses, 35, 157-170.
3. Brockhoff, A., Behrens, M., Niv, M. Y., and Meyerhof, W.* (2010) Structural requirements of bitter taste receptor activation. Proc. Natl. Acad. Sci. USA., 107, 11110-11115.
4. Born, S., Levit, A., Niv, M. Y, Meyerhof, W., and Behrens, M.* (2013) The human bitter taste receptor TAS2R10 is tailored to accommodate numerous diverse ligands. J. Neurosci., 33, 201-213.
5. Behrens, M.*, Korsching, S. I., and Meyerhof, W. (2014) Tuning properties of avian and frog bitter taste receptors dynamically fit gene repertoire sizes. Mol. Biol. Evol., 31, 3216-3227.
6. Behrens, M.*, Blank, K., and Meyerhof, W. (2017) Blends of non-caloric sweeteners saccharin and cyclamate show reduced off-taste due to TAS2R bitter receptor inhibition. Cell Chem. Biol., 24, 1199-1204.
7. Prandi, S., Voigt, A., Meyerhof, W., and Behrens, M.* (2018) Expression profiling of Tas2r genes reveals a complex pattern along the mouse GI tract and the presence of Tas2r131 in a subset of intestinal Paneth cells. Cell. Mol. Life Sci., 75, 49-65.
8. Nowak, S., Di Pizio, A., Levit, A., Niv, M. Y., Meyerhof, W., and Behrens, M.* (2018) Reengineering the ligand sensitivity of the broadly tuned human bitter taste receptor TAS2R14. Biochim. Biophys. Acta, Gen. Subj., 1862, 2162-2173.
9. Di Pizio, A., Waterloo, L. A. W., Brox, R., Loeber, S., Weikert, D., Behrens, M.*, Gmeiner, P.*, and Niv, M. Y.* (2020) Rational design of agonists for the bitter taste receptor TAS2R14: from modeling to bench and back. Cell. Mol. Life Sci., 77, 531-542.
10. Behrens, M.*, Di Pizio, A., Redel, U., Meyerhof, W.*, and Korsching, S. I.* (2021) At the root of T2R gene evolution: Recognition profiles of coelacanth and zebrafish bitter receptors. Genome Biol. Evol., 13: evaa264
*=corresponding author
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