As officially drawn up and notarized on April 03, 1918, the Ministry of State of the Royal House and the Ministries for Domestic and Foreign Affairs established the research institute as public trust. Appointed Founding Director was Privy Councilor Professor Theodor Paul, MD, Chair of the Department of Pharmacology and Applied Chemistry at the University of Munich, who initiated the foundation. After inflation devalued the endowment fund in 1923, the 'Deutsche Forschungsanstalt für Lebensmittelchemie' (DFA; German Research Centre for Food Chemistry) continued to operate closely linked to the University's Applied Chemistry Laboratory.
Founding Professor Theodor Paul died on September 30, 1928. His successor, Professor Dr. Benno Bleyer, Chair of the Department of Pharmacology and Food Chemistry at the University of Munich, started to further develop the institute on April 01, 1928.
Military air strikes obliterated the institute and almost all its property.
Professor Dr. Benno Bleyer, Director of the institute, died on November 24, 1945.
The institute continued to be home to scientists in makeshift accommodations in Dachau, Munich-Nymphenburg, and in Munich-Schwabing.
Professor Dr. S. Walter Souci, who provisionally managed the institute as acting chairman, was appointed director on July 16, 1946.
The Bavarian Ministry for Education and Cultural Affairs and the German Federal Ministry for Food, Agriculture and Forestry provide funding for the institute.
The scientists of the institute move into the newly constructed laboratories in the Wenschow Building in Munich-Schwabing.
After serving as director of the institute for 23 years, Professor Siegfried Walter Souci retired in 1968.
On February 01, Professor Dr. Hans-Dieter Belitz, chair of the Institute for Food Chemistry at the Technical University of Munich, was appointed director of the institute.
Since January 01, the institute receives financing pursuant to a framework agreement between the German Federal Government and the German States on the joint funding of scientific projects according to Article 91b GG (German Constitutional Law). The institute moved into new laboratories in the building of the Department of Chemistry, Biology and Geosciences of the Technical University of Munich.
After a serious illness, the institute director Professor Dr. Hans-Dieter Belitz passed away on March 31.
On August 01, Professor Dr. Peter Schieberle, Chair of Food Chemistry at the Technical University of Munich, was appointed director of the institute.
In April, the institute moved into their new laboratories on the TUM Life Science Campus Weihenstephan in Freising.
On March 31, Professor Dr. Peter Schieberle retired. As of August 15, Professor Dr. Thomas Hofmann, Vice President of the Research & Innovation of the Technical University of Munich and Chair of Food Chemistry and Molecular Sensory Science at the Life Science Campus Weihenstephan was appointed the new director of the institute.
Accounting for its new structural organization as well as scientific and strategic focus, the institute was renamed on September 07 into 'Leibniz-Institute for Food Systems Biology at the Technical University of Munich (in short: Leibniz-LSB@TUM).
On Friday, 15th June 2018, the institute celebrated its 100-Year Anniversary.
Movie: 100 Jahre Molekulare Lebensmittel- und Ernährungsforschung (100 Years of Molecular Food and Nutrition Research)
October 17, 2018, the Board of Trustees of the Technical University of Munich (TUM) has elected Prof. Thomas Hofmann (50) as the new President of TUM. On October 1, 2019, Hofmann will take over from Prof. Wolfgang A. Herrmann, whose far-reaching reforms in his 23-year tenure saw TUM rise to international top level.